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Low-Frequency Blood Group Antigens in Switzerland
Author(s) -
Christoph Gassner,
Frauke Degenhardt,
Stefan Meyer,
Caren Vollmert,
Nadine Trost,
Kathrin Neuenschwander,
Yvonne Merki,
C. Portmann,
Sonja Sigurdardottir,
Antigoni Zorbas,
Charlotte Engström,
Jochen Gottschalk,
Soraya Amar El Dusouqui,
S. Waldvogel-Abramovski,
Emmanuel Rigal,
JeanDaniel Tissot,
Caroline Tinguely,
S.M. Mauvais,
Amira Sarraj,
D. Bessero,
M. Stalder,
Laura Infanti,
Andreas Buser,
Jörg Sigle,
Tina Weingand,
D Castelli,
M.C. Braisch,
Jutta Thierbach,
Sonja Heer,
T. Schulzki,
Michael Krawczak,
André Franke,
Beat M. Frey
Publication year - 2018
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000490714
Subject(s) - genotyping , blood group antigens , allele frequency , immunology , allele , antigen , minor allele frequency , population , genotype , blood transfusion , red blood cell , medicine , snp , snp genotyping , biology , single nucleotide polymorphism , genetics , gene , environmental health
High-frequency blood group antigens (HFA) are present in >90% of the human population, according to some reports even in >99% of individuals. Therefore, patients lacking HFA may become challenging for transfusion support because compatible blood is hardly found, and if the patient carries alloantibodies, the cross-match will be positive with virtual every red cell unit tested.

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