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Effect of Human Coronavirus OC43 Structural and Accessory Proteins on the Transcriptional Activation of Antiviral Response Elements
Author(s) -
Meshal Beidas,
Wassim Chehadeh
Publication year - 2018
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000490566
Subject(s) - hek 293 cells , biology , sendai virus , luciferase , interferon , ns5a , response element , microbiology and biotechnology , virology , coronavirus , gene , virus , gene expression , promoter , genetics , transfection , hepatitis c virus , hepacivirus , medicine , disease , covid-19 , pathology , infectious disease (medical specialty)
The molecular mechanisms underlying the pathogenesis of human coronavirus OC43 (HCoV-OC43) infection are poorly understood. In this study, we investigated the ability of HCoV-OC43 to antagonize the transcriptional activation of antiviral response elements.

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