The Landscape of Circular RNA Expression Profiles in Papillary Thyroid Carcinoma Based on RNA Sequencing | Zendy

Xiabin Lan | Zendy; Jiajie Xu | Zendy; Chao Chen | Zendy; Chuanming Zheng | Zendy; Jiafeng Wang | Zendy; Jun Cao | Zendy; Xuhang Zhu | Zendy; Minghua Ge | Zendy

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The Landscape of Circular RNA Expression Profiles in Papillary Thyroid Carcinoma Based on RNA Sequencing

Author(s) -

Xiabin Lan,

Jiajie Xu,

Chao Chen,

Chuanming Zheng,

Jiafeng Wang,

Jun Cao,

Xuhang Zhu,

Minghua Ge

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000490188

Subject(s) - kegg , circular rna , carcinogenesis , biology , microrna , computational biology , rna , thyroid carcinoma , thyroid cancer , papillary thyroid cancer , gene , gene expression , genetics , bioinformatics , cancer , gene ontology , thyroid

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. However, the molecular mechanisms responsible for its tumorigenesis and progression remain largely unknown. Circular RNA (circRNA) is a novel type of noncoding RNA that can serve as an ideal biomarker due to its stability. Recent evidence suggests that circRNAs play important roles in tumorigenesis. This study aims to investigate circRNA expression profiles and their potential biological functions in PTC.

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