HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer | Zendy

Ertao Zhai | Zendy; Wei Liang | Zendy; Yi Lin | Zendy; Linlin Huang | Zendy; Xin He | Zendy; Shirong Cai | Zendy; Jianhui Chen | Zendy; Ning Zhang | Zendy; Jiali Li | Zendy; Qiuyang Zhang | Zendy; Yulong He | Zendy; Zhirong Zeng | Zendy; Minhu Chen | Zendy; Lixia Xu | Zendy; Sui Peng | Zendy

Open Access

HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer

Author(s) -

Ertao Zhai,

Wei Liang,

Yi Lin,

Linlin Huang,

Xin He,

Shirong Cai,

Jianhui Chen,

Ning Zhang,

Jiali Li,

Qiuyang Zhang,

Yulong He,

Zhirong Zeng,

Minhu Chen,

Lixia Xu,

Sui Peng

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000490080

Subject(s) - autocrine signalling , apoptosis , biology , cell growth , cancer research , oncogene , cancer , cancer cell , cell , hsp70 , viability assay , cell cycle , heat shock protein , microbiology and biotechnology , receptor , biochemistry , genetics , gene

HSP70/HSP90-organizing protein (HOP) is an adaptor protein that mediates heat shock protein 70 (HSP70) and HSP90 folding. HOP can be secreted by cancer cells and promote malignant cell growth in an autocrine manner. Here, we studied its role in gastric cancer (GC).

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