Association of Five Snps in Cytotoxic T-Lymphocyte Antigen 4 and Cancer Susceptibility: Evidence from 67 Studies | Zendy

Min Fang | Zendy; WenCheng Huang | Zendy; Dan Mo | Zendy; Wei Zhao | Zendy; Rongyong Huang | Zendy

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Association of Five Snps in Cytotoxic T-Lymphocyte Antigen 4 and Cancer Susceptibility: Evidence from 67 Studies

Author(s) -

Min Fang,

WenCheng Huang,

Dan Mo,

Wei Zhao,

Rongyong Huang

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000489953

Subject(s) - medicine , odds ratio , oncology , breast cancer , meta analysis , cancer , single nucleotide polymorphism , confidence interval , pancreatic cancer , genetic predisposition , publication bias , head and neck cancer , population , immunology , disease , genotype , biology , genetics , gene , environmental health

CTLA-4 polymorphisms are associated with susceptibility to various cancers, but the results are often conflicting. Hence, we performed a comprehensive meta-analysis to quantitatively investigate the association between CTLA-4 polymorphisms (rs231775, rs4553808rs5742909, rs3087243 or rs733618) and cancer risk.

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