Open AccessTherapeutic Effect of CD4+CD25+ Regulatory T Cells Amplified In Vitro on Experimental Autoimmune Neuritis in Rats
Author(s) -
Feng-Jie Wang,
Dan Cui,
Wei-Dong Qian
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000489919
Subject(s) - il 2 receptor , flow cytometry , medicine , foxp3 , immunology , neuritis , cd28 , endocrinology , pharmacology , immune system , t cell , psychiatry
This study aimed to explore whether the adoptive transfusion of autologous CD4+CD25+ regulatory T cells (CD4+CD25+ Tregs) has a therapeutic effect on Experimental autoimmune neuritis (EAN) model rats, and it provides new experimental and theoretical bases for the immunotherapy of Guillain-Barre syndrome (GBS).
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