Treatment of Cutaneous Ulcers with Multilayered Mixed Sheets of Autologous Fibroblasts and Peripheral Blood Mononuclear Cells | Zendy

Takahiro Mizoguchi | Zendy; Koji Ueno | Zendy; Yuriko Takeuchi | Zendy; Makoto Samura | Zendy; Ryo Suzuki | Zendy; Tomoaki Murata | Zendy; Tohru Hosoyama | Zendy; Noriyasu Morikage | Zendy; Kimikazu Hamano | Zendy

Open Access

Treatment of Cutaneous Ulcers with Multilayered Mixed Sheets of Autologous Fibroblasts and Peripheral Blood Mononuclear Cells

Author(s) -

Takahiro Mizoguchi,

Koji Ueno,

Yuriko Takeuchi,

Makoto Samura,

Ryo Suzuki,

Tomoaki Murata,

Tohru Hosoyama,

Noriyasu Morikage,

Kimikazu Hamano

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000489767

Subject(s) - peripheral blood mononuclear cell , medicine , peripheral , peripheral blood , pathology , chemistry , immunology , in vitro , biochemistry

We have developed a mixed-cell sheet consisting of autologous fibroblasts and peripheral blood mononuclear cells with a high potency for angiogenesis and wound healing against refractory cutaneous ulcers in mouse and rabbit models. To increase the effectiveness of the mixed sheet, we developed a multilayered mixed sheet.

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