Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search | Zendy

Vladimir Kogan | Zendy; Joshua Millstein | Zendy; Stephanie J. London | Zendy; Carole Ober | Zendy; Steven R. White | Zendy; Edward T. Naureckas | Zendy; W. James Gauderman | Zendy; Daniel J. Jackson | Zendy; Albino BarrazaVillarreal | Zendy; Isabelle Romieu | Zendy; Benjamin A. Raby | Zendy; Carrie V. Breton | Zendy

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Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search

Author(s) -

Vladimir Kogan,

Joshua Millstein,

Stephanie J. London,

Carole Ober,

Steven R. White,

Edward T. Naureckas,

W. James Gauderman,

Daniel J. Jackson,

Albino BarrazaVillarreal,

Isabelle Romieu,

Benjamin A. Raby,

Carrie V. Breton

Publication year - 2018

Publication title -

human heredity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.423

H-Index - 62

eISSN - 1423-0062

pISSN - 0001-5652

DOI - 10.1159/000489765

Subject(s) - epigenetics , single nucleotide polymorphism , cpg site , genetics , promoter , gene , snp , dna methylation , biology , genotype , gene expression

There is evidence to suggest that asthma pathogenesis is affected by both genetic and epigenetic variation independently, and there is some evidence to suggest that genetic-epigenetic interactions affect risk of asthma. However, little research has been done to identify such interactions on a genome-wide scale. The aim of this studies was to identify genes with genetic-epigenetic interactions associated with asthma.

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