Peptidomic Analysis of Endometrial Tissue from Patients with Ovarian Endometriosis | Zendy

Yunping Xue | Zendy; Pengfei Xu | Zendy; Sujuan Xu | Zendy; Kai Xue | Zendy; Lingling Xu | Zendy; Jie Chen | Zendy; Juan Xu | Zendy; Xiaoyan Shi | Zendy; Qian Li | Zendy; Lin Gu | Zendy

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Peptidomic Analysis of Endometrial Tissue from Patients with Ovarian Endometriosis

Author(s) -

Yunping Xue,

Pengfei Xu,

Sujuan Xu,

Kai Xue,

Lingling Xu,

Jie Chen,

Juan Xu,

Xiaoyan Shi,

Qian Li,

Lin Gu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000489753

Subject(s) - endometriosis , pathogenesis , stromal cell , tandem mass tag , fold change , peptide , proteomics , western blot , biology , medicine , chemistry , cancer research , quantitative proteomics , gene expression , biochemistry , gene

Ovarian endometriosis (OvE) is ovarian cyst that is lined with endometrial tissue. They are found in 17-44% of women with endometriosis. Their clinical manifestations include pelvic pain, dysmenorrhea, dyspareunia, and infertility. Although the incidence of OvE has increased yearly, the exact pathogenesis of OvE is still unclear. We used peptidomics, an emerging branch of proteomics, to identify differentially expressed peptides in order to determine the possible roles of these peptides in the pathogenesis of OvE.

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