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SCCA, TSGF, and the Long Non-Coding RNA AC007271.3 are Effective Biomarkers for Diagnosing Oral Squamous Cell Carcinoma
Author(s) -
Tingru Shao,
Jiaxin Huang,
Zenan Zheng,
Qingqing Wu,
Tiancai Liu,
Xiaozhi Lv
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000489741
Subject(s) - long non coding rna , microarray analysis techniques , receiver operating characteristic , stage (stratigraphy) , carcinoma , microarray , basal cell , cancer , medicine , cancer research , cell , biomarker , oncology , biology , downregulation and upregulation , gene , gene expression , paleontology , biochemistry , genetics
Oral squamous cell carcinoma (OSCC) is one of the most lethal malignancies worldwide and the most common type of oral cancer, characterized by invasive growth, frequent regional metastases, high recurrence, and poor prognosis. In the current study, we investigated the use of long non-coding RNAs (lncRNAs), tumor-specific growth factor (TSGF), and squamous cell carcinoma antigen (SCCA) as potential biomarkers for OSCC screening.

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