MicroRNA-449a Inhibition Protects H9C2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Targeting the Notch-1 Signaling Pathway | Zendy

Jing Cheng | Zendy; Qianfu Wu | Zendy; Rong Lv | Zendy; Li Huang | Zendy; Banglong Xu | Zendy; Xianbao Wang | Zendy; Aihua Chen | Zendy; Fei He | Zendy

Open Access

MicroRNA-449a Inhibition Protects H9C2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Targeting the Notch-1 Signaling Pathway

Author(s) -

Jing Cheng,

Qianfu Wu,

Rong Lv,

Li Huang,

Banglong Xu,

Xianbao Wang,

Aihua Chen,

Fei He

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000489686

Subject(s) - propidium iodide , notch signaling pathway , apoptosis , microbiology and biotechnology , annexin , signal transduction , chemistry , biology , transfection , programmed cell death , flow cytometry , cell culture , biochemistry , genetics

The present study aimed to detect the expression of miR-449a and investigate the effect of miR-449a on cell injury in cardiomyocytes subjected to hypoxia/ reoxygenation (H/R) and its underlying mechanisms.

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