MiR-27b Promotes Muscle Development by Inhibiting MDFI Expression
Author(s) -
Lianjie Hou,
Jian Xu,
Yiren Jiao,
Huaqin Li,
Zhicheng Pan,
Junli Duan,
Ting Gu,
Ching Yuan Hu,
Chong Wang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000489595
Subject(s) - myogenesis , skeletal muscle , microbiology and biotechnology , myocyte , regeneration (biology) , biology , microrna , cell growth , western blot , gene , endocrinology , genetics
Skeletal muscle plays an essential role in the body movement. However, injuries to the skeletal muscle are common. Lifelong maintenance of skeletal muscle function largely depends on preserving the regenerative capacity of muscle. Muscle satellite cells proliferation, differentiation, and myoblast fusion play an important role in muscle regeneration after injury. Therefore, understanding of the mechanisms associated with muscle development during muscle regeneration is essential for devising the alternative treatments for muscle injury in the future.
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