Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot Specificity | Zendy

Hua Guan | Zendy; Yali Zhang | Zendy; Shoucui Gao | Zendy; Liang Bai | Zendy; Sihai Zhao | Zendy; Xian Wu Cheng | Zendy; Jianglin Fan | Zendy; Enqi Liu | Zendy

Open Access

Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot Specificity

Author(s) -

Hua Guan,

Yali Zhang,

Shoucui Gao,

Liang Bai,

Sihai Zhao,

Xian Wu Cheng,

Jianglin Fan,

Enqi Liu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000489545

Subject(s) - adipocyte , adipogenesis , white adipose tissue , adipose tissue , medicine , glut4 , endocrinology , wnt signaling pathway , adipose tissue macrophages , biology , 3t3 l1 , microbiology and biotechnology , adiponectin , signal transduction , insulin , insulin resistance

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that acts as soluble modulators of Wnt signaling. Given the substantial rise in obesity, depot-specific fat accumulation and its associated diseases like diabetes, it is important to understand the molecular basis of depot-specific adipocyte differentiation. In the current study, we investigated the expression of SFRP4 in both subcutaneous and visceral adipose tissue in terms of their differentiation.

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