Mitochondrial Perturbation Contributing to Cognitive Decline in Streptozotocin-Induced Type 1 Diabetic Rats
Author(s) -
Yu Zhou,
Siheng Lian,
Jin Zhang,
Donghai Lin,
Caihua Huang,
Libin Liu,
Zhou Chen
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000489243
Subject(s) - streptozotocin , mitochondrion , cognitive decline , cognition , morris water navigation task , neuroscience , metabolomics , biology , endocrinology , medicine , diabetes mellitus , microbiology and biotechnology , bioinformatics , disease , dementia
Mitochondrial perturbation is a well-established cause of cognitive decline, but as yet it is unclear how mitochondria-associated neuronal abnormalities in type 1 diabetic (T1DM) brain contribute to cognitive decline.
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