Alterations in Serum MicroRNA Profile During Hemodialysis - Potential Biological Implications
Author(s) -
Dorota Trzybulska,
Dag Eckersten,
Aleksander Giwercman,
Anders Christensson,
Christos Tsatsanis
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000488737
Subject(s) - microrna , hemodialysis , biology , gene expression profiling , biological pathway , fold change , downregulation and upregulation , homeostasis , bioinformatics , gene expression , cancer research , medicine , computational biology , endocrinology , gene , genetics
Hemodialysis implies significant alterations in the profile of serum components. microRNAs (miRNAs) are present in the human serum and are considered to target distant tissues where they can regulate gene expression, thus affecting homeostasis. Whether hemodialysis alters the profile of miRNAs in the serum is not known.
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