Prognostic Significance of LncRNA PVT1 and Its Potential Target Gene Network in Human Cancers: a Comprehensive Inquiry Based Upon 21 Cancer Types and 9972 Cases
Author(s) -
RongQuan He,
Meijiao Qin,
Peng Lin,
Yihuan Luo,
Jie Ma,
Hong Yang,
Xiaohua Hu,
Gang Chen
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000488627
Subject(s) - pvt1 , kegg , biology , cancer , cancer research , gene , long non coding rna , gene expression , bioinformatics , computational biology , transcriptome , genetics , rna
Whether the level of long noncoding RNA plasmacytoma variant translocation 1 gene (lncRNA PVT1) expression influences the clinical development and outcome of human cancers has not been thoroughly elucidated to date. Inconsistencies still exist regarding the associations between PVT1 and the clinicopathological features, including patient survival data. Additionally, the regulatory mechanism of PVT1 among human cancers remains unclear.
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