Soluble Receptor for Advanced Glycation End Products (sRAGE) is Up-Regulated in Multiple Sclerosis Patients Treated with Interferon β-1a
Author(s) -
Mehrali Rahimi,
Sarah Saadat Aghabozorg Afjeh,
Mir Davood Omrani,
Shahram ArsangJang,
Maziar Ganji,
Rezvan Noroozi,
Mohammad Taheri,
Soudeh GhafouriFard
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000488622
Subject(s) - multiple sclerosis , rage (emotion) , glycation , pathogenesis , medicine , receptor , immune system , immunology , expanded disability status scale , inflammation , endocrinology , biology , neuroscience
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system. Considering the role of immune system in its pathogenesis, researchers have focused on evaluation of the expression of immune-related genes or proteins in MS patients. Among proteins whose participation in inflammatory process has been documented is the receptor for advanced glycation end products (RAGE).
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