Human Platelet Antigens in Brazilian Multiethnic Populations: Occurrence of Regional Variation and Frequency in a Large Urban Center (Belo Horizonte)
Author(s) -
Maria Clara Fernandes da Silva Malta,
Lucas Gabriel Tavares de Oliveira,
Luísa Ferreira Barreiros,
Dilson Rocha do Amaral,
Marina Lobato Martins
Publication year - 2018
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000488469
Subject(s) - allele frequency , genotype , dendrogram , allele , biology , genetic variation , demography , regional variation , immunology , population , genetics , genetic diversity , gene , sociology , law , political science
The frequency of human platelet antigens (HPA) varies according to ethnicity, which causes differences in the morbidity of alloimmune and autoimmune thrombocytopenic disorders in different populations. Studies on HPA frequencies in Brazil have reported differences among Brazilian populations produced by the diverse degrees of admixture throughout the country.
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