Calcium/Calmodulin-Dependent Protein Kinase IV Mediates IFN-γ-Induced Immune Behaviors in Skeletal Muscle Cells | Zendy

Ruicai Gu | Zendy; Maochao Ding | Zendy; Dandan Shi | Zendy; Tao Huang | Zendy; Mengxia Guo | Zendy; Lei Yu | Zendy; Jijie Hu | Zendy; Wenhua Huang | Zendy; Hua Liao | Zendy

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Calcium/Calmodulin-Dependent Protein Kinase IV Mediates IFN-γ-Induced Immune Behaviors in Skeletal Muscle Cells

Author(s) -

Ruicai Gu,

Maochao Ding,

Dandan Shi,

Tao Huang,

Mengxia Guo,

Lei Yu,

Jijie Hu,

Wenhua Huang,

Hua Liao

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000488435

Subject(s) - gene knockdown , myogenesis , microbiology and biotechnology , c2c12 , biology , chemokine , myocyte , creb , protein kinase a , small hairpin rna , immune system , signal transduction , kinase , cell culture , immunology , transcription factor , biochemistry , genetics , gene

Whether calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a role in regulating immunologic features of muscle cells in inflammatory environment, as it does for immune cells, remains mostly unknown. In this study, we investigated the influence of endogenous CaMKIV on the immunological characteristics of myoblasts and myotubes received IFN-γ stimulation.

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