Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer’s Disease Model
Author(s) -
Tingting Xu,
Yang Zhang,
Jiayang He,
Dan Luo,
Yi Luo,
Yijie Wang,
Wei Liu,
Jun Wu,
Wei Zhao,
Jiansong Fang,
Li Guan,
Shun Huang,
Hong Wang,
Li Lin,
Shijie Zhang,
Qi Wang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000488414
Subject(s) - endoplasmic reticulum , morris water navigation task , hippocampus , neuroprotection , amyloid beta , unfolded protein response , blot , amyloid precursor protein , medicine , neurotrophic factors , alzheimer's disease , neuroscience , endocrinology , pharmacology , chemistry , biology , microbiology and biotechnology , disease , biochemistry , receptor , gene
Alzheimer disease (AD) is a common neurodegenerative disease that is characterized by the deposition of beta-amyloid peptide and formation of intracellular neurofibrillary tangles. Due to the failure of various clinical trials of novel drugs for AD, effective drugs for AD treatment are urgently required.
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