LncRNA SNHG16 Functions as an Oncogene by Sponging MiR-4518 and Up-Regulating PRMT5 Expression in Glioma | Zendy

Ye-Fen Lu | Zendy; Xueli Cai | Zendy; Zhengzheng Li | Zendy; Jing Lv | Zendy; Yi-an Xiang | Zendy; Jianjun Chen | Zendy; Weijing Chen | Zendy; Wei-Yan Sun | Zendy; Xiumei Liu | Zendy; Jianbo Chen | Zendy

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LncRNA SNHG16 Functions as an Oncogene by Sponging MiR-4518 and Up-Regulating PRMT5 Expression in Glioma

Author(s) -

Ye-Fen Lu,

Xueli Cai,

Zhengzheng Li,

Jing Lv,

Yi-an Xiang,

Jianjun Chen,

Weijing Chen,

Wei-Yan Sun,

Xiumei Liu,

Jianbo Chen

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000487974

Subject(s) - glioma , biology , gene knockdown , viability assay , cancer research , pi3k/akt/mtor pathway , oncogene , long non coding rna , protein kinase b , cell growth , signal transduction , cell , apoptosis , gene , microbiology and biotechnology , rna , genetics , cell cycle

Long noncoding RNAs (lncRNAs) have recently emerged as novel and potentially promising therapeutic targets in various cancers. However, the expression pattern and biological function of lncRNAs in glioma remain largely elusive. In the present study, we investigated the functional role of an lncRNA, small nucleolar RNA host gene 16 (SNHG16), in glioma.

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