The Long Intergenic Noncoding RNA 00707 Promotes Lung Adenocarcinoma Cell Proliferation and Migration by Regulating Cdc42
Author(s) -
Tianshi Ma,
Hongwei Ma,
Zigui Zou,
Xuezhi He,
Yanhua Liu,
You Shuai,
Min Xie,
Zhihong Zhang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000487693
Subject(s) - biology , gene knockdown , carcinogenesis , cancer research , long non coding rna , cell cycle , cell growth , oncogene , microarray analysis techniques , cell , lung cancer , apoptosis , cancer , gene expression , downregulation and upregulation , pathology , gene , medicine , genetics
Lung cancer (LC) is a serious disease with high morbidity and mortality. Long noncoding RNAs (lncRNAs) have garnered attention because they participate in diverse human disorders, including cancer. Our study examined the long intergenic noncoding RNA 00707 (LINC00707). The effects of LINC00707 on lung adenocarcinoma (LAD) and molecular mechanisms are unclear. This study is aimed to investigate the role of LINC00707 in the malignant processes of LAD.
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