Type I Diabetic Akita Mouse Model is Characterized by Abnormal Cardiac Deformation During Early Stages of Diabetic Cardiomyopathy with Speckle-Tracking Based Strain Imaging | Zendy

Yingchao Zhou | Zendy; Hong Xiao | Zendy; Jianfei Wu | Zendy; Lingfeng Zha | Zendy; Mengchen Zhou | Zendy; Qianqian Li | Zendy; Mengru Wang | Zendy; Shumei Shi | Zendy; Yanze Li | Zendy; Liangkun Lyu | Zendy; Qing K. Wang | Zendy; Xin Tu | Zendy; Qiulun Lu | Zendy

Open Access

Type I Diabetic Akita Mouse Model is Characterized by Abnormal Cardiac Deformation During Early Stages of Diabetic Cardiomyopathy with Speckle-Tracking Based Strain Imaging

Author(s) -

Yingchao Zhou,

Hong Xiao,

Jianfei Wu,

Lingfeng Zha,

Mengchen Zhou,

Qianqian Li,

Mengru Wang,

Shumei Shi,

Yanze Li,

Liangkun Lyu,

Qing K. Wang,

Xin Tu,

Qiulun Lu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000487690

Subject(s) - diabetic cardiomyopathy , medicine , diabetes mellitus , heart failure , cardiology , cardiomyopathy , speckle tracking echocardiography , speckle pattern , endocrinology , ejection fraction , artificial intelligence , computer science

Diabetes mellitus (DM) has been demonstrated to have a strong association with heart failure. Conventional echocardiographic analysis cannot sensitively monitor cardiac dysfunction in type I diabetic Akita hearts, but the phenotype of heart failure is observed in molecular levels during the early stages.

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