Endoscopic Removal of Two Esophageal Over-The-Scope Clips with Cold Saline Solution Technique

A 51-year-old man with a T4N1M0 gastric adenocarcinoma underwent neoadjuvant chemotherapy and total gastrectomy with Roux-en-Y esophagojejunostomy. Due to clinical worsening in the immediate postoperative period, an abdominal computed tomography was performed, revealing an empyema and a fistulous tract between the distal esophagus and the pleural cavity. The patient was initially treated with broad spectrum antibiotics and total parenteral nutrition, without clinical improvement. Endoscopy was then performed with identification of the esophageal orifice of the fistula and it was decided to proceed to endoscopic closure of the fistula with an over-the-scope clip (OTSC). Destruction of the epithelial lining of the accessible part of the fistulous tract with argon plasma coagulation was conducted followed by the application of an OTSC. A second OTSC was placed to ensure complete closure of the fistula. Reassessment with gastrografin transit showed no leakage of contrast. The patient resumed oral feeding with good tolerance and was discharged 10 days after the endoscopic procedure without any complications. Six weeks later he presented with dysphagia, regurgitation, and weight loss. Endoscopy documented the presence of the 2 OTSC attached to each other and partially migrated to the lumen, causing luminal obstruction at the level of the esophagojejunal anastomosis. After an unsuccessful attempt to remove them with a conventional foreign-body grasper (Fig. 1), a second attempt was performed by submerging the clips for 1 min with cold saline solution previously kept in the refrigerator (Fig. 2; online suppl. Video 1, see www.karger.com/doi/10.1159/000487152), and with successive twisting maneuvers of the corners of the OTSC with a grasper it was possible to remove them “en bloc” with little resistance (Fig. 3). Thereafter, the patient repeated a gastrografin transit with adequate contrast progression and was discharged uneventfully. The OTSC, commonly known as the “bear claw,” can provide full-thickness closure of open defects up to 2–3 cm with greater compressive force than through-thescope clips. Consequently, OTSC have the ability to close