Transplanted Dental Pulp Stem Cells Migrate to Injured Area and Express Neural Markers in a Rat Model of Cerebral Ischemia | Zendy

Xuemei Zhang | Zendy; Yinglian Zhou | Zendy; Hulun Li | Zendy; Rui Wang | Zendy; Dan Yang | Zendy; Bing Li | Zendy; Xiaofang Cao | Zendy; Jin Fu | Zendy

Open Access

Transplanted Dental Pulp Stem Cells Migrate to Injured Area and Express Neural Markers in a Rat Model of Cerebral Ischemia

Author(s) -

Xuemei Zhang,

Yinglian Zhou,

Hulun Li,

Rui Wang,

Dan Yang,

Bing Li,

Xiaofang Cao,

Jin Fu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000486772

Subject(s) - dental pulp stem cells , medicine , neural stem cell , transplantation , ischemia , stem cell , pathology , neural crest , stem cell therapy , regeneration (biology) , infarction , surgery , biology , microbiology and biotechnology , mesenchymal stem cell , embryo , myocardial infarction

Ischemic stroke is a major cause of disability and mortality worldwide, while effective restorative treatments are limited at present. Stem cell transplantation holds therapeutic potential for ischemic vascular diseases and may provide an opportunity for neural regeneration. Dental pulp stem cells (DPSCs) origin from neural crest and have neuro-ectodermal features including proliferation and multilineage differentiation potentials.

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