Phage Abp1 Rescues Human Cells and Mice from Infection by Pan-Drug Resistant Acinetobacter Baumannii | Zendy

Supeng Yin | Zendy; Guangtao Huang | Zendy; Yulong Zhang | Zendy; Bei Jiang | Zendy; Zichen Yang | Zendy; Zhi-Wei Dong | Zendy; Bo You | Zendy; Zhiqiang Yuan | Zendy; Fuquan Hu | Zendy; Yan Zhao | Zendy; Yizhi Peng | Zendy

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Phage Abp1 Rescues Human Cells and Mice from Infection by Pan-Drug Resistant Acinetobacter Baumannii

Author(s) -

Supeng Yin,

Guangtao Huang,

Yulong Zhang,

Bei Jiang,

Zichen Yang,

Zhi-Wei Dong,

Bo You,

Zhiqiang Yuan,

Fuquan Hu,

Yan Zhao,

Yizhi Peng

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000486117

Subject(s) - acinetobacter baumannii , hela , microbiology and biotechnology , cytotoxicity , phage therapy , bacteriophage , drug , lysogenic cycle , drug resistance , biology , virology , chemistry , bacteria , cell , in vitro , escherichia coli , pharmacology , pseudomonas aeruginosa , biochemistry , genetics , gene

As an "ESKAPE" pathogen, Acinetobacter baumannii is one of the leading causes of drug-resistant infections in humans. Phage therapy may be a useful strategy in treating infections caused by drug-resistant A. baumannii. Among 21 phage strains that were isolated and described earlier, we investigated the therapeutic efficacy of Abp1 because of its relatively wide host range.

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