Open AccessThe IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
Author(s) -
Takaaki Nakada,
Petch Wacharasint,
James A. Russell,
John H. Boyd,
Emiri Nakada,
Simone A. Thair,
Tadanaga Shimada,
Keith R. Walley
Publication year - 2018
Publication title -
journal of innate immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.078
H-Index - 64
eISSN - 1662-8128
pISSN - 1662-811X
DOI - 10.1159/000486104
Subject(s) - septic shock , polymorphism (computer science) , outcome (game theory) , medicine , biology , genetics , immunology , sepsis , genotype , gene , mathematics , mathematical economics
The IL10 family of genes includes crucial immune regulators. We tested the hypothesis that single nucleotide polymorphisms (SNPs) in IL10, IL19, IL20, and IL24 of the IL10 family gene cluster alter the clinical outcome of septic shock.
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