Sesamin Protects Against Cardiac Remodeling Via Sirt3/ROS Pathway | Zendy

Di Fan | Zendy; Zheng Yang | Zendy; Fang-Yuan Liu | Zendy; YaGe Jin | Zendy; Ning Zhang | Zendy; Jian Ni | Zendy; Yuan Yuan | Zendy; Hai-Han Liao | Zendy; Qingqing Wu | Zendy; Man Xu | Zendy; Wei Deng | Zendy; Qizhu Tang | Zendy

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Sesamin Protects Against Cardiac Remodeling Via Sirt3/ROS Pathway

Author(s) -

Di Fan,

Zheng Yang,

Fang-Yuan Liu,

YaGe Jin,

Ning Zhang,

Jian Ni,

Yuan Yuan,

Hai-Han Liao,

Qingqing Wu,

Man Xu,

Wei Deng,

Qizhu Tang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000486026

Subject(s) - sesamin , sirt3 , sod2 , medicine , pharmacology , oxidative stress , cardiac fibrosis , ventricular remodeling , endocrinology , sirtuin , fibrosis , chemistry , superoxide dismutase , heart failure , biochemistry , traditional medicine , acetylation , gene

Cardiac remodeling is associated with oxidative stress. Sesamin, a well-known antioxidant from sesamin seeds, have been used extensively as traditional health foods. However, there is little known about the effect of sesamin on cardiac remodeling. Therefore, the present study aimed to determine whether sesamin could protect against cardiac remodeling and to clarify potential molecular mechanisms.

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