CircRNA Expression Profile in Early-Stage Lung Adenocarcinoma Patients | Zendy

Jiangmin Zhao | Zendy; Le Li | Zendy; Qian Wang | Zendy; Hongxiu Han | Zendy; Qing Zhan | Zendy; Ming Xu | Zendy

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CircRNA Expression Profile in Early-Stage Lung Adenocarcinoma Patients

Author(s) -

Jiangmin Zhao,

Le Li,

Qian Wang,

Hongxiu Han,

Qing Zhan,

Ming Xu

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485953

Subject(s) - adenocarcinoma , lung cancer , microarray , circular rna , microrna , biology , stage (stratigraphy) , microarray analysis techniques , lung , computational biology , disease , cancer research , cancer , bioinformatics , gene , pathology , medicine , gene expression , genetics , paleontology

Lung adenocarcinoma, a form of non-small cell lung cancer with high lethality at an advanced stage, is becoming more common in women, non- or never-smokers, and even young adults. At present, there are still no effective early diagnosis methods for patients to be cured in a timely manner. Circular RNAs (circRNAs), which are stable and conserved non-coding RNA in mammalian cells, have been reported to be widely involved in the processes of cancer disease. However, it is still a puzzle as to which specific circRNAs are involved in the development of early-stage lung adenocarcinoma.

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