Exosomes from MiR-126-Overexpressing Adscs Are Therapeutic in Relieving Acute Myocardial Ischaemic Injury | Zendy

Qiancheng Luo | Zendy; Dongfeng Guo | Zendy; Guorong Liu | Zendy; Guo Chen | Zendy; Hang Min | Zendy; Mingming Jin | Zendy

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Exosomes from MiR-126-Overexpressing Adscs Are Therapeutic in Relieving Acute Myocardial Ischaemic Injury

Author(s) -

Qiancheng Luo,

Dongfeng Guo,

Guorong Liu,

Guo Chen,

Hang Min,

Mingming Jin

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485949

Subject(s) - microvesicles , exosome , medicine , fibrosis , angiogenesis , inflammation , cancer research , stem cell , myocardial infarction , microrna , immunology , pathology , microbiology and biotechnology , biology , biochemistry , gene

Recent studies have indicated that exosomes play an important role in adipose-derived stem cell (ADSC) transplant-mediated ischaemic heart disease therapy. However, the treatment effect is not obvious. The aim of this study is to investigate whether ADSC-derived exosomes enriched with microRNA (miR)-126 have a more protective effect on acute myocardial infarction (AMI).

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