Increased Small Intestinal Permeability during Severe Acute Exacerbations of COPD | Zendy

Roy T.M. Sprooten | Zendy; Kaatje Lenaerts | Zendy; Dionne C.W. Braeken | Zendy; Ilvy Grimbergen | Zendy; Erica P.A. Rutten | Zendy; Emiel F.�M. Wouters | Zendy; Gernot Rohde | Zendy

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Increased Small Intestinal Permeability during Severe Acute Exacerbations of COPD

Author(s) -

Roy T.M. Sprooten,

Kaatje Lenaerts,

Dionne C.W. Braeken,

Ilvy Grimbergen,

Erica P.A. Rutten,

Emiel F.�M. Wouters,

Gernot Rohde

Publication year - 2018

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000485935

Subject(s) - medicine , copd , intestinal permeability , lactulose , gastroenterology , exacerbation , endocrinology

Disturbances of intestinal integrity, manifested by increased gastro-intestinal (GI) permeability, have been found in chronic obstructive pulmonary disease (COPD) patients during physical activity, often associated with intermittent hypoxic periods. Evidence about extrapulmonary organ disturbances, especially of the GI tract, during hospitalised acute exacerbation of COPD (AE-COPD) with hypoxaemic respiratory failure (RF) is lacking.

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