MiR-124 Inhibits Growth and Enhances Radiation-Induced Apoptosis in Non-Small Cell Lung Cancer by Inhibiting STAT3 | Zendy

Mengjie Wang | Zendy; Bi Meng | Zendy; Yangchen Liu | Zendy; Jingwen Yu | Zendy; Qiaoyun Chen | Zendy

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MiR-124 Inhibits Growth and Enhances Radiation-Induced Apoptosis in Non-Small Cell Lung Cancer by Inhibiting STAT3

Author(s) -

Mengjie Wang,

Bi Meng,

Yangchen Liu,

Jingwen Yu,

Qiaoyun Chen

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485907

Subject(s) - radiosensitivity , stat3 , apoptosis , cancer research , radioresistance , cell growth , microrna , cell culture , stat protein , biology , a549 cell , flow cytometry , gene silencing , lung cancer , microbiology and biotechnology , medicine , radiation therapy , pathology , gene , genetics

A growing body of evidence indicates that the abnormal expression of microRNAs (miRNAs) play an important role in sensitizing the cellular response to ionizing radiation (IR). The aim of this study was to investigate whether the expression of miR-124 correlated with radiosensitivity in the context of non-small-cell lung carcinoma (NSCLC).

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