Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer | Zendy

Hefei Wang | Zendy; Bing Liu | Zendy; Jing Wang | Zendy; Jinglin Li | Zendy; Ying Gong | Zendy; Sisi Li | Zendy; Chunli Wang | Zendy; Bai Cui | Zendy; Xiaoyuan Xue | Zendy; MengYing Yang | Zendy; Wenjun Fan | Zendy; Zhi-Jie Kang | Zendy; Kamran I. Muhammad | Zendy; Jie Xu | Zendy; Pengfei Tian | Zendy; Yuanyuan Luo | Zendy; Zhijie Hou | Zendy; Lin Dong | Zendy; Ren YanLing | Zendy; Man Li | Zendy; Qingping Wen | Zendy; Wei Cheng | Zendy; Lingzhi Xu | Zendy; Ling Wang | Zendy; Quentin Liu | Zendy

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Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer

Author(s) -

Hefei Wang,

Bing Liu,

Jing Wang,

Jinglin Li,

Ying Gong,

Sisi Li,

Chunli Wang,

Bai Cui,

Xiaoyuan Xue,

MengYing Yang,

Wenjun Fan,

Zhi-Jie Kang,

Kamran I. Muhammad,

Jie Xu,

Pengfei Tian,

Yuanyuan Luo,

Zhijie Hou,

Lin Dong,

Ren YanLing,

Man Li,

Qingping Wen,

Wei Cheng,

Lingzhi Xu,

Ling Wang,

Quentin Liu

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485405

Subject(s) - homeobox protein nanog , aspirin , colorectal cancer , cancer stem cell , cancer research , cancer , metastasis , cancer cell , medicine , biology , embryonic stem cell , induced pluripotent stem cell , biochemistry , gene

Cancer stem cells (CSCs) are considered to be responsible for tumor relapse and metastasis, which serve as a potential therapeutic target for cancer. Aspirin has been shown to reduce cancer risk and mortality, particularly in colorectal cancer. However, the CSCs-suppressing effect of aspirin and its relevant mechanisms in colorectal cancer remain unclear.

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