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Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio as Prognostic Predictors for Hepatocellular Carcinoma Patients with Various Treatments: a Meta-Analysis and Systematic Review
Author(s) -
Jun Zheng,
Jianye Cai,
Hui Li,
Kaining Zeng,
Liying He,
Hongyuan Fu,
Jiebin Zhang,
Liang Chen,
Jia Yao,
Yingcai Zhang,
Yang� Yang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000485396
Subject(s) - medicine , hepatocellular carcinoma , hazard ratio , neutrophil to lymphocyte ratio , confidence interval , meta analysis , gastroenterology , subgroup analysis , lymphocyte , oncology
Systemic inflammatory response (SIR) is widely considered as a preoperative risk factor for hepatocellular carcinoma (HCC) outcomes. The neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), two of the prognostic indices, have been investigated in post-therapeutic recurrence and survival of HCC. Here, we quantify the prognostic value of these two biomarkers and evaluate their consistency in different HCC therapies.

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