Melatonin-Induced Changes in Cytosolic Calcium Might be Responsible for Apoptosis Induction in Tumour Cells | Zendy

Barbora Chovancova | Zendy; Soňa Hudecová | Zendy; Lubomira Lencesova | Zendy; Petr Babula | Zendy; Ingeborg Režuchová | Zendy; Adela Penesová | Zendy; Marian Grman | Zendy; Roman Moravčík | Zendy; Michal Zeman | Zendy; Oľga Križanová | Zendy

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Melatonin-Induced Changes in Cytosolic Calcium Might be Responsible for Apoptosis Induction in Tumour Cells

Author(s) -

Barbora Chovancova,

Soňa Hudecová,

Lubomira Lencesova,

Petr Babula,

Ingeborg Režuchová,

Adela Penesová,

Marian Grman,

Roman Moravčík,

Michal Zeman,

Oľga Križanová

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485290

Subject(s) - melatonin , apoptosis , microbiology and biotechnology , cell culture , chemistry , biology , endocrinology , biochemistry , genetics

Melatonin is a hormone transferring information about duration of darkness to the organism and is known to modulate several signaling pathways in the cells, e.g. generation of endoplasmic reticulum stress, oxidative status of the cells, etc. Melatonin has been shown to exert antiproliferative and cytotoxic effects on various human cancers. We proposed that this hormone can differently affect tumour cells and healthy cells.

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