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β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells
Author(s) -
Wendan Yu,
Li Li,
Fufu Zheng,
Wenjing Yang,
Shilei Zhao,
Chunfang Tian,
Wenwen Yin,
YiMing Chen,
Wei Guo,
Lijuan Zou,
Wuguo Deng
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000485013
Subject(s) - wnt signaling pathway , cancer research , catenin , cell growth , lung cancer , apoptosis , beta catenin , proliferating cell nuclear antigen , gene knockdown , immunohistochemistry , adenocarcinoma , biology , cancer , chemistry , signal transduction , medicine , pathology , microbiology and biotechnology , immunology , biochemistry , genetics
β-catenin is an integral component of the canonical Wnt signaling pathway, and its mutations are an autosomal recessive cause of colorectal cancer (CRC), medulloblastoma (MDB), and ovarian cancer. Nevertheless, little is known about its function in lung cancers.

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