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Association of Functional Genetic Variants of HOTAIR with Hepatocellular Carcinoma (HCC) Susceptibility in a Chinese Population
Author(s) -
Hao Li,
Xianmei Tang,
Yangchen Liu,
Weizhen Li,
Qiaoyun Chen,
Yan Pan
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000485011
Subject(s) - hotair , single nucleotide polymorphism , hepatocellular carcinoma , genotype , allele , long non coding rna , biology , case control study , cancer research , medicine , oncology , genetics , gene , rna
The HOX transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA (lncRNA), plays an important role in the pathogenesis and progression of multiple tumors. The aim of the present study was to evaluate whether common single nucleotide polymorphisms (SNPs) in HOTAIR are related to hepatocellular carcinoma (HCC) susceptibility in a Chinese population.

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