Trolline Ameliorates Liver Fibrosis by Inhibiting the NF-κB Pathway, Promoting HSC Apoptosis and Suppressing Autophagy | Zendy

Facheng Bai | Zendy; Quanfang Huang | Zendy; Jinlan Nie | Zendy; Shengjuan Lu | Zendy; Chunyuan Lu | Zendy; Xunshuai Zhu | Zendy; Yuxin Wang | Zendy; Lang Zhuo | Zendy; Zhongpeng Lu | Zendy; Xing Lin | Zendy

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Trolline Ameliorates Liver Fibrosis by Inhibiting the NF-κB Pathway, Promoting HSC Apoptosis and Suppressing Autophagy

Author(s) -

Facheng Bai,

Quanfang Huang,

Jinlan Nie,

Shengjuan Lu,

Chunyuan Lu,

Xunshuai Zhu,

Yuxin Wang,

Lang Zhuo,

Zhongpeng Lu,

Xing Lin

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485009

Subject(s) - autophagy , apoptosis , hepatic stellate cell , ccl4 , fibrosis , chemistry , nf κb , vacuole , pharmacology , cancer research , biology , endocrinology , pathology , medicine , biochemistry , carbon tetrachloride , organic chemistry , cytoplasm

Previous studies have shown that trolline possesses various forms of pharmacological activity, including antibacterial and antiviral potency. The present paper addressed the putative hepatoprotective effects of trolline.

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