Rapid Induction of Osteogenic Markers in Mesenchymal Stem Cells by Adipose-Derived Stromal Vascular Fraction Cells | Zendy

JungWon Choi | Zendy; Sunhye Shin | Zendy; Chang Youn Lee | Zendy; Jiyun Lee | Zendy; HyangHee Seo | Zendy; Soyeon Lim | Zendy; Seahyoung Lee | Zendy; Il-Kwon Kim | Zendy; Hoon-Bum Lee | Zendy; Sang Woo Kim | Zendy; KiChul Hwang | Zendy

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Rapid Induction of Osteogenic Markers in Mesenchymal Stem Cells by Adipose-Derived Stromal Vascular Fraction Cells

Author(s) -

JungWon Choi,

Sunhye Shin,

Chang Youn Lee,

Jiyun Lee,

HyangHee Seo,

Soyeon Lim,

Seahyoung Lee,

Il-Kwon Kim,

Hoon-Bum Lee,

Sang Woo Kim,

KiChul Hwang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000484582

Subject(s) - stromal vascular fraction , mesenchymal stem cell , paracrine signalling , microbiology and biotechnology , adipose tissue , stem cell , stem cell transplantation for articular cartilage repair , bone marrow , regenerative medicine , population , stromal cell , adipogenesis , biology , immunology , adult stem cell , medicine , endothelial stem cell , cancer research , endocrinology , in vitro , biochemistry , receptor , environmental health

Stromal vascular fraction (SVF) cells are a mixed cell population, and their regenerative capacity has been validated in various therapeutic models. The purpose of this study was to investigate the regenerative mechanisms utilized by implanted SVF cells. Using an in vitro co-culture system, we sought to determine whether SVF implantation into impaired tissue affects endogenous mesenchymal stem cell (MSC) differentiation; MSCs can differentiate into a variety of cell types, and they have a strong regenerative capacity despite their low numbers in impaired tissue.

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