LncRNA UCA1 Promotes Mitochondrial Function of Bladder Cancer via the MiR-195/ARL2 Signaling Pathway
Author(s) -
Hui-Jin Li,
Xiaomin Sun,
Zhengkun Li,
Qianwen Yin,
Huan Pang,
Jingjing Pan,
Xu Li,
Wei Chen
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000484507
Subject(s) - bladder cancer , cancer research , signal transduction , microrna , function (biology) , apoptosis , mitochondrion , microbiology and biotechnology , chemistry , cancer , medicine , biology , gene , biochemistry
This study aims to identify whether Urothelial Cancer Associated 1 (UCA1) regulates mitochondrial metabolic reprogramming in bladder cancer, and to explore how UCA1 participates in mitochondrial metabolism by the UCA1/miR-195/ARL2 signaling pathway; these findings may be aid in the development of tumor diagnostic and therapeutic strategies.
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