Physiological Signatures of Dual Embryonic Origins in Mouse Skull Vault | Zendy

Bo Hu | Zendy; Taofen Wu | Zendy; Yongxu Zhao | Zendy; Guangtao Xu | Zendy; Ruilin Shen | Zendy; Guiqian Chen | Zendy

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Physiological Signatures of Dual Embryonic Origins in Mouse Skull Vault

Author(s) -

Bo Hu,

Taofen Wu,

Yongxu Zhao,

Guangtao Xu,

Ruilin Shen,

Guiqian Chen

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000484496

Subject(s) - cranial vault , calvaria , neural crest , intramembranous ossification , biology , skull , parietal bone , mesoderm , anatomy , cranial neural crest , microbiology and biotechnology , frontal bone , lateral plate mesoderm , osteoblast , neuroscience , embryonic stem cell , genetics , gene , embryo , in vitro

The mammalian skull vault is a highly regulated structure and consists of several membrane bones of different tissue origins (e.g. neural crest derived frontal bone and mesoderm derived parietal bone). Although membrane bones form through intramembranous ossification, neural crest derived frontal bone has superior osteoblast activity and bone regeneration ability, triggering a novel conception for craniofacial reconstruction and bone regeneration called endogenous calvarial regeneration. However, a comprehensive landscape of the genes and signaling pathways involved in this process is not clear.

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