Aberrant Expression of Long Non-Coding RNAs in Newly Diagnosed Type 2 Diabetes Indicates Potential Roles in Chronic Inflammation and Insulin Resistance | Zendy

Xiaoli Wang | Zendy; Xiangyun Chang | Zendy; Peipei Zhang | Zendy; Ling Fan | Zendy; Ting Zhou | Zendy; Kan Sun | Zendy

Open Access

Aberrant Expression of Long Non-Coding RNAs in Newly Diagnosed Type 2 Diabetes Indicates Potential Roles in Chronic Inflammation and Insulin Resistance

Author(s) -

Xiaoli Wang,

Xiangyun Chang,

Peipei Zhang,

Ling Fan,

Ting Zhou,

Kan Sun

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000484388

Subject(s) - insulin resistance , type 2 diabetes , pathogenesis , microarray , inflammation , biology , microarray analysis techniques , long non coding rna , gene , downregulation and upregulation , fold change , bioinformatics , immune system , gene expression , diabetes mellitus , medicine , computational biology , immunology , genetics , endocrinology

Long non-coding RNAs (lncRNAs) have emerged as key players in several biological processes and complex diseases. The risk of type 2 diabetes (T2D) is determined by a combination of environmental factors and genetic susceptibility. The purpose of this study was to identify aberrant lncRNAs involved in T2D pathogenesis.

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