Open AccessMembranous and Cytoplasmic Expression of PD-L1 in Ovarian Cancer Cells
Author(s) -
Qiu-Xia Qu,
Fang Xie,
Qin Huang,
Xue-Guang Zhang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000484109
Subject(s) - cancer research , ovarian cancer , pd l1 , cancer cell , flow cytometry , t cell , biology , cd8 , pi3k/akt/mtor pathway , immune system , cancer , chemistry , signal transduction , microbiology and biotechnology , immunotherapy , immunology , genetics
Expression of programmed death-ligand 1 (PD-L1) on tumor cells represents a powerful immune evasion pathway, but the role of intracellular or cytoplasmic PD-L1 has not been investigated in ovarian cancer cells.
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