Gene Microarray Integrated with High-Throughput Proteomics for the Discovery of Transthyretin in Rhabdomyolysis-Induced Acute Kidney Injury
Author(s) -
Li Ou,
Xiaodong Geng,
Qian Ma,
Weiwei Wang,
Ran Liu,
Zhong Yin,
Siyang Wang,
Guangyan Cai,
Xiangmei Chen,
Quan Hong
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000484028
Subject(s) - transthyretin , apoptosis , acute kidney injury , microbiology and biotechnology , microarray analysis techniques , blot , microarray , viability assay , biology , chemistry , gene expression , cancer research , gene , medicine , biochemistry , endocrinology
Rhabdomyolysis, one of the leading causes of acute kidney injury (AKI), develops after trauma, drug toxicity, infections, burns, and physical exertion. The aim of this study was to investigate differences in gene and protein expression to elucidate the pathogenesis of rhabdomyolysis (RM)-induced AKI.
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