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α1-Antitrypsin deficiency (AATD) predisposes to chronic obstructive pulmonary disease (COPD). In COPD unrelated to AATD, the role of a higher blood eosinophil count in disease and subsequent personalization of therapy has recently received much attention. We sought to investigate this concept in patients with AATD-associated COPD.

respiration

ICS Use May Modify FEV&lt;sub&gt;1&lt;/sub&gt; Decline in α&lt;sub&gt;1&lt;/sub&gt;-Antitrypsin Deficiency Patients with Relatively High Blood Eosinophils