α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage
Author(s) -
Chengmei Lv,
Surendra Maharjan,
Qingqing Wang,
Yongxin Sun,
Xu Han,
Shan Wang,
Zhengchun Mao,
Yanming Xin,
Bing Zhang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000481840
Subject(s) - neuroprotection , viability assay , pharmacology , oxidative stress , western blot , gene knockdown , brain damage , reperfusion injury , medicine , chemistry , ischemia , apoptosis , biochemistry , endocrinology , gene
Alpha-lipoic acid (α-LA) has been demonstrated to be protective against cerebral ischemia injury. Herein, we investigate the neuroprotective effect and underlying mechanisms of α-LA.
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