The Long Non-Coding RNA XIST Interacted with MiR-124 to Modulate Bladder Cancer Growth, Invasion and Migration by Targeting Androgen Receptor (AR) | Zendy

Yaoyao Xiong | Zendy; Long Wang | Zendy; Yuan Li | Zendy; Minfeng Chen | Zendy; Wei He | Zendy; Lin Qi | Zendy

Open Access

The Long Non-Coding RNA XIST Interacted with MiR-124 to Modulate Bladder Cancer Growth, Invasion and Migration by Targeting Androgen Receptor (AR)

Author(s) -

Yaoyao Xiong,

Long Wang,

Yuan Li,

Minfeng Chen,

Wei He,

Lin Qi

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000480419

Subject(s) - xist , gene knockdown , androgen receptor , long non coding rna , bladder cancer , cancer research , biology , microrna , cancer , downregulation and upregulation , prostate cancer , cell culture , x inactivation , gene , genetics , x chromosome

Long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is involved in the progression of several tumors. The interaction between lncRNA and miRNA or miRNA's target genes is reported to play crucial roles in malignancy. In addition, Androgen receptor (AR) is considered to be involved in bladder cancer progression. In this study, we investigated the role of XIST in human bladder cancer and its interaction with miR-124 and AR.

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