Theranostics of Neuroendocrine Tumors
Author(s) -
Sze Ting Lee,
Harshad Kulkarni,
Aviral Singh,
Richard P. Baum
Publication year - 2017
Publication title -
visceral medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.598
H-Index - 17
eISSN - 2297-475X
pISSN - 2297-4725
DOI - 10.1159/000480383
Subject(s) - radionuclide therapy , neuroendocrine tumors , somatostatin receptor , somatostatin , medicine , peptide receptor , positron emission tomography , quality of life (healthcare) , oncology , toxicity , nuclear medicine , receptor , nursing
Somatostatin receptor positron emission tomography/computed tomography using 68 Ga-labeled somatostatin analogs is the mainstay for the evaluation of receptor status in neuroendocrine tumors (NETs). This translates towards better therapy options, with increasing evidence of peptide receptor radionuclide therapy (PRRT) as the treatment of choice for advanced or progressive NETs. There are benefits in progression-free and overall survival as well as a significant improvement in clinical condition. In patients with progressive NETs, fractionated, personalized PRRT results in good therapeutic responses with no significant severe hematological and/or renal toxicity, thus improving quality of life.
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