Exogenous Hydrogen Peroxide Induces Lipid Raft-Mediated STAT-6 Activation in T Cells
Author(s) -
Hee Ja Kim,
Jiwoo Lim,
Young-Soon Jang,
EuiCheol Shin,
Hyung-Ran Kim,
JuYoung Seoh,
Ji Soo Lee,
Soon Nam Lee,
Jihee Lee Kang,
YounHee Choi
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000480210
Subject(s) - lipid raft , phosphorylation , jurkat cells , microbiology and biotechnology , stat , chemistry , signal transduction , cellular differentiation , biology , t cell , immune system , biochemistry , stat3 , immunology , gene
CD4+ T cells are a critical component of the adaptive immune response. While the mechanisms controlling the differentiation of the Th1, Th17, and regulatory T cell subsets from naïve CD4+ T cells are well described, the factors that induce Th2 differentiation are still largely unknown.
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