Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells | Zendy

Huiying Shi | Zendy; Xinyan Zhao | Zendy; Zhen Ding | Zendy; Chaoqun Han | Zendy; Ye Jiang | Zendy; Wei Qian | Zendy; Rong Lin | Zendy; Xiaohua Hou | Zendy

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Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells

Author(s) -

Huiying Shi,

Xinyan Zhao,

Zhen Ding,

Chaoqun Han,

Ye Jiang,

Wei Qian,

Rong Lin,

Xiaohua Hou

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000480184

Subject(s) - autophagy , vacuole , becn1 , microbiology and biotechnology , amino acid , chemistry , bag3 , sodium–hydrogen antiporter , sequestosome 1 , biochemistry , alanine , biology , apoptosis , cytoplasm , sodium , organic chemistry

Dysfunctional autophagy has been reported to be associated with aberrant intestinal metabolism. Amino acids can regulate autophagic activity in intestinal epithelial cells (IECs). Na+/H+-exchanger 3 (NHE3) has been found to participate in the absorption of amino acids in the intestine, but whether NHE3 is involved in the regulation of autophagy in IECs is unclear.

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